Thursday, November 28, 2019

Anthropology 101 Research Paper Essay Example

Anthropology 101 Research Paper Essay Example Anthropology 101 Research Paper Essay Anthropology 101 Research Paper Essay Komron Sabbagh Prof. Rowe Anthropology 101 March 25, 2013 Elderly Human â€Å"Y† Chromosome The unearthing and examination of a tremendously infrequent African American â€Å"Y† chromosome goes back in time with regards to the most recent common ancestor for the â€Å"Y† chromosome ancestry to 338,000 years ago. This period exists even older than the age of the most eldest known structurally contemporary human fossils. University of Arizona geneticists have revealed the most ancient known hereditary subdivision of the human â€Å"Y† chromosome the genetic factor which determines the male sex. The new differing pedigree, which was discovered in a male human being who presented his DNA to â€Å"Family Tree DNA†, a company which concentrates on DNA investigation to locate family roots, separated from the â€Å"Y† chromosome tree before the very first presence of physically current individuals in the record of fossils. These effects are printed in the American Journal of Human Genetics. Michael Hammer of the University of Arizona’s department of ecology and evolutionary biology stated that, Our analysis indicates this lineage diverged from previously known Y chromosomes about 338,000 ago, a time when anatomically modern humans had not yet evolved. This pushes back the time the last common Y chromosome ancestor lived by almost 70 percent. Dissimilar to the added human chromosomes, the common â€Å"Y† chromosome doesn’t barter heritable information with other chromosomes; this makes it a lot more straightforward and scientists can truly discover familial associations amid modern ancestries. If two â€Å"Y† chromosomes transmit an identical mutation, it is most likely since they divide a communal forefather at some particular period in the precedent. The further mutations which differ amongst two Y chromosomes, the farther back in history the mutual antecedent existed. Initially, a DNA sample acquired from an African American existing in South Carolina was succumbed to the National Geographic Genographic Project. When none of the hereditary indicators used to dispense ancestries to identified â€Å"Y† chromosome consortiums were found, the DNA sample was guided to â€Å"Family Tree DNA† for organizing. Fernando Mendez, who is a postdoctoral scholar in Hammers laboratory, controlled the attempt to investigate the DNA sequence, which comprised of over 240,000 base pairs of the Y chromosome. Hammer claimed that the most striking feature of this research is that a consumer genetic testing company identified a lineage that didnt fit anywhere on the existing Y chromosome tree, even though the tree had been constructed based on perhaps a half-million individuals or more. Nobody expected to find anything like this. At around 300,000 years ago; this was the period of time in which the Neanderthals are thought to have fragmented from the familial human descent. It was not until more than 100,000 years in the future that functionally recent humans seem to be in the fossil record. They vary from the more antiquated forms by a more frivolously constructed skeleton; this includes a lesser face pushed underneath a tall forehead, the lack of a cranial ridge and slighter chins. Hammer stated that t he recently exposed â€Å"Y† chromosome dissimilarity is tremendously occasional. Through the use of great databank explorations, his group ultimately was capable of discovering a comparable chromosome in the Mbo, which is a populace living in a petite region of western Cameroon in the sub-Saharan part of Africa. This was surprising because previously the most diverged branches of the Y chromosome were found in traditional hunter-gatherer populations such as Pygmies and the click-speaking KhoeSan, who are considered to be the most diverged human populations living today. Instead, the sample matched the Y chromosome DNA of 11 men, who all came from a very small region of western Cameroon, Hammer explains. And the sequences of those individuals are variable, so its not like they all descended from the same grandfather. Hammer restraints against prevalent notions of mitochondrial Eve or Y chromosome Adam which propose that all of humanity was derived from precisely one couple of individuals that lived at a particular point in human biological evolution. There has been too much emphasis on this in the past, Hammer says. It is a misconception that the genealogy of a single genetic region reflects population divergence. Instead, our results suggest that there are pockets of genetically isolated communities that together preserve a great deal of human diversity. Nevertheless, Hammer explains that, It is likely that other divergent lineages will be found, whether in Africa or among African-Americans in the U. S. and that some of these may further increase the age of the Y chromosome ree. He further clarifies: There has been a lot of hype with people trying to trace their Y chromosome to different tribes, but this individual from South Carolina can say he did it. The investigation originated by the mutual labors of a private business, the â€Å"Family Tree DNA,† the struggles of a resident scientist, Bonnie Schrack, and the research proficiencies at the UA. Human Y Chromosome Much Older Than Previously Thought. ScienceDaily. ScienceDaily, 04 Mar. 2013. Web. 26 Mar. 2013.

Sunday, November 24, 2019

Free Essays on Woman Administration

The leaders of today come in all shapes and sizes. Gone is the image of a middle-aged white male behind a desk, directing his followers in an authoritarian manner. We have come to realize that leaders are distinct in regards to age, gender, race, ethnic origin, physical abilities, religious belief, sexual orientation, and other perceived differences. Diversity means understanding and valuing the differences in each other. Leadership for the 21st Century requires us to appreciate all aspects of diversity since we are truly becoming a global community. To achieve diversity one must have increased awareness, education, and the ability to evaluate old and new information. Increased awareness is to remember that bias and assumptions are normal. Education is the process of learning about people who are different; learn with an open mind. We evaluate old and new information and decide which views to let go, and which ones to keep. The Promotable Woman (the new leader of the 90s) acts out her own convictions rather than merely reacting to people and situations. She focuses on living up to her own expectations, not other people ¡Ã‚ ¦s expectations for her. She doesn ¡Ã‚ ¦t need to acquiesce passively to others ¡Ã‚ ¦ demands nor automatically rebel against them. She is her own person. Norma Carr-Ruffino Do women lead differently than men? This question is often presented among leadership scholars. The answer is no ¡K and yes. Both women and men are capable of inspiring others, making decisions, resolving conflicts, and accomplishing assorted tasks. However, the manner in which they do so is different. Women and men exemplify distinct leadership styles because of their gender differences. According to the female gender role, women are considered to have more social qualities (e.g., they are perceived to be emotional, sensitive, supporting, gentle, kind, and affectionate), whereas men are assumed to possess more agentic qualities (e.g., independent,... Free Essays on Woman Administration Free Essays on Woman Administration The leaders of today come in all shapes and sizes. Gone is the image of a middle-aged white male behind a desk, directing his followers in an authoritarian manner. We have come to realize that leaders are distinct in regards to age, gender, race, ethnic origin, physical abilities, religious belief, sexual orientation, and other perceived differences. Diversity means understanding and valuing the differences in each other. Leadership for the 21st Century requires us to appreciate all aspects of diversity since we are truly becoming a global community. To achieve diversity one must have increased awareness, education, and the ability to evaluate old and new information. Increased awareness is to remember that bias and assumptions are normal. Education is the process of learning about people who are different; learn with an open mind. We evaluate old and new information and decide which views to let go, and which ones to keep. The Promotable Woman (the new leader of the 90s) acts out her own convictions rather than merely reacting to people and situations. She focuses on living up to her own expectations, not other people ¡Ã‚ ¦s expectations for her. She doesn ¡Ã‚ ¦t need to acquiesce passively to others ¡Ã‚ ¦ demands nor automatically rebel against them. She is her own person. Norma Carr-Ruffino Do women lead differently than men? This question is often presented among leadership scholars. The answer is no ¡K and yes. Both women and men are capable of inspiring others, making decisions, resolving conflicts, and accomplishing assorted tasks. However, the manner in which they do so is different. Women and men exemplify distinct leadership styles because of their gender differences. According to the female gender role, women are considered to have more social qualities (e.g., they are perceived to be emotional, sensitive, supporting, gentle, kind, and affectionate), whereas men are assumed to possess more agentic qualities (e.g., independent,...

Thursday, November 21, 2019

Projects and their management Essay Example | Topics and Well Written Essays - 1000 words

Projects and their management - Essay Example The organization has a team of 3 staff members charged with the duty to place students in a year in the job market that can contribute to the professional development of the students. This service makes the existence of SEC placement team more relevant in the face of the employers’ increasing demand for experience both for old and new graduates. To better its services, SPT could take advantage of the increasing use of web tools among students to make the placement services more efficient and convenient. Even though this would be a costly endeavor for a start-up placement enterprise, SPT longstanding existence can allow it use the revenue that it has accumulated in the past to build this web product intended to make placement exercises efficient and convenient and efficient for students and for SPT itself. SPT project will follow the conventional software process that is typical of all IT projects. The phases will include: business specification, system design, product development, testing, system implementation and maintenance and evaluation. Business specification will entail elicitation and assessment of the user and system requirements. Design will entail translation of the defined requirements into a set of design models, out of which the involve team will choose the best design. Development will entail translation of the design model that the developers settle on into program codes whose operation will follow the user requirements without compromising on the system requirements. Testing will involve assessment of whether the developed product functions as per the user-supplied requirements. Implementation will involve use of the developed system in the production environment, where students and other intended end-users will try executing their routinely duties to satisfy their r espective needs. Maintenance and evaluation will involve caring for the

Wednesday, November 20, 2019

English 2 - DB 5 Essay Example | Topics and Well Written Essays - 250 words

English 2 - DB 5 - Essay Example I have learned to pay more attention to pre-writing research in order to have enough valid information for own research. Researching can be time consuming; however, it shows different points of view on the same issue which helps to develop own opinion and express it in writing. There is a great difference between oral communication and written communication. While it is possible to make mistakes and correct them immediately while speaking, there is a need to spend additional time on revising the paper to make sure that there are no ambiguities in writing.. Any research paper needs an outline to follow to cover all necessary points. Inaccurate expressions can confuse the reader; working on my last written assignment I read it to my friend to make sure that it sounded clearly. The process of peer revision is very helpful because it gives an objective feedback about ones work; I cannot say that I can assess my writing totally objectively as I always treat it as my achievement. In this way, help of my peers can be really valuable to see ho I can improve my writing. Overall, I understand that I need to work hard to become a better writer. Currently I lack some experience in research writing and this course is really helpful because it complexly improves my writing skills. Now I see the difference between relevant and irrelevant sources of information and understand why I need to spend more time on selecting the best sources for my research. I am learning to keep my writing clear and concise and any writing assignment greatly contributes to my writing and researching

Monday, November 18, 2019

The need for the return of prayer in public schools Research Paper

The need for the return of prayer in public schools - Research Paper Example Corruption in the modern society is the highest and the technology has facilitated the criminals in developing new ways of achieving their malicious intentions. This includes mobile photography and the use of facebook to retrieve people’s personal information and black-mailing them. This has fundamentally been so because of a lack of emphasis on practicing religion and religious studies on both national and international level. Today in most of the schools in the advanced countries, the curriculum has been redesigned in a way that it is to much extent, technology oriented, but has very less to convey on religious grounds. Although there has been a large emphasis on the inclusion of ethical concepts like corporate social responsibility into the business on a global scale, yet concrete results have not yet been obtained given the lack of ethical considerations in the roots of entrepreneurs’ schooling. There is a severe need for the return of prayer in public schools in order to make the students ethically conscious so that they turn into responsible and considerate professionals in their practical life. Prayers were considered a significant part of the American schools’ curriculum until between 1962 and 1963, when the Supreme Court decided to ban prayer in the schools. (Squidoo LLC, 2010). â€Å"On June 25, l962, 39 million students were forbidden to do what they and their predecessors had been doing since the founding of our nation.† (Bergel, 1988, para. 2). Since then, prayer have been altogether eliminated from the public schools in the US. Although this attempt of Supreme Court has met with huge criticism, yet the decision of Supreme Court stayed and the prayers continued to remain banned ever since. As a result of elimination of prayer from the public schools, it is not only the students that have suffered, but also their parents and teachers have not managed to escape the curse. (Squidoo LLC, 2010) quotes

Friday, November 15, 2019

The Use of Mixl1 in Ex Vivo and Chimeric Organ Regeneration

The Use of Mixl1 in Ex Vivo and Chimeric Organ Regeneration Anokhi Kashiparekh   TA: Goheun Kim Regenerative medicine is a field in biology that uses the underlying cell properties of differentiated growth to create entire tissues and organs from that cell. Regeneration in its true form, applies human pluripotent stem cell (hPSCs) differentiation, to make new organs like the natural regeneration of the human liver or that of the zebrafish heart (Mostoway et al, 2013). A very useful area for such a technique is the organ donation and replacement discipline. One of the greatest challenges for organ replacement is the shortage of organs donated for the cause. This is where the field of regenerative medicine can come in use. If the cells of the person in need of the organs can differentiate in a way that fills up the niche left by the diseased or missing organ, there could be a remarkable decrease in the need for organ transplantation and organ rejection. However, the development of the human organs is a gradual process and may take longer than the time the patient has to survive. A tactic to increase the speediness and the efficiency of organ regeneration is to manipulate certain genes to promote either ex vivo differentiation or differentiation in a chimeric host with a faster developmental time than humans. Specific genes can be engineered to perform specific functions, like prompting apoptosis using the Bcl-2 gene or assessing mesodermal markers using Wnt3 (Wu et al, 2016). Inducing Mixl1, the endoderm and mesoderm formation transcription factor, can play an important role in generating organs from induced pluripotent stem cells (iPSCs). Mixl1 plays an important role in chimeric and ex vivo regeneration models; although further research is required on the viability of these models. The Mixl1 transcription factor binds to the Mix gene and is a part of the hox gene family that codes for homeodomain proteins. The most important function of the Mixl1 is the regulation of cell fate and differentiation during the developmental stages of an organisms life. It regulates the formation of the endodermal and mesodermal layers and consequently can be used to manipulate hPSCs towards a particular lineage of growth. This principal property of the Mixl1 gene, as well its interactions with other genes, has been the focus of genetic regenerative medicine, in order to understand the role and consequent use of said genes. Various experiments have tried to incorporate the Mixl1 system in stem cell growth but two of the most widely known models are the ex vivo regeneration model and the chimeric model. Both of these models rely on the property of Mixl1 to guide iPSCs towards either endodermal or mesodermal fate. The basic difference between these models is the environment in which these cells are allowed to differentiate. The ex vivo model allows cell differentiation and growth outside an organism, generally in a laboratory. It is a widely preferred model due to the fact that cells from an organism can be extracted, cultured in a lab and placed back in the same organism. Each step in the experiment can be tracked and monitored and all the cells are cultured in a sterile environment. Thus, the cells placed back inside the animal are safe from potential bacteria or viruses. However, this also means that the organs generated from this may not be compatible with the surrounding tissue when introduced in an organisms body, due to the lack of interaction with other cells. Ex vivo culture of cells and ultimate organ regeneration is a step towards solving the problem of limited availability of desired cells. This ex vivo model of organ regeneration makes use of different substrates to recreate a natural differentiating environment for the cultured cells. However most times it is hard to push the hPSCs towards a particular lineage of growth, i.e. mesodermal or endodermal. The Mixl1 gene with its property to establish cell fate, is useful in resolving this. The forced expression of Mixl1 in hPSCs, in the right environment, with particular substrates and specific protein mediums, can promote ex vivo cell differentiation. Ex vivo culture, with connection to the Mixl1 gene is efficient due to the control over time of forced expression of the Mixl1 gene as well as external monitoring of the growth. Liu et al (2011)3 established this by using Là °Ã‚ Ã‚ Ã‚ °5ÃŽÂ ²1 and Là °Ã‚ Ã‚ Ã‚ °6ÃŽÂ ²1 protein ligands to promote Mixl1 induced hPSCs, in a BMP4 medium. The procedure included purifying polypeptides, culturing the hPSCs and allowing them to differentiate. The results showed that the differentiation of cells peaked on the third (to) fourth day of culture when both the LÃŽÂ ±5ÃŽÂ ²1 and Là °Ã‚ Ã‚ Ã‚ °6ÃŽÂ ²1 protein ligands were used. This gradual growth was tracked using immunofluorescence and analyzed by flow cytometry. The results of this experiment encompass both the usefulness as well as the disadvantages of an ex vivo regeneration of organs using Mixl1. The biggest challenge encountered in an ex vivo organ regeneration model is the limited number of substrates that the hPSCs can use and differentiate into a mesodermal lineage. In various cases, Mixl1 is induced unsuccessfully. This is due to the high substance substrate specificity of the iPSCs that do not survive long enough for Mixl1 to express and differentiate. Another case seen in Liu et al was the very minute expression of Mixl1 when cultured with various other individual ligands, showing that this procedure also requires the correct combination of substrates. Various agencies have also raised ethical concerns over culturing animal cells in labs. The obtaining of cells, external media and substrates from animal bodies is cited as animal abuse (cruelty). To minimize the use of animal products, a more specific area of the ex vivo model has been developed, called the xeno-free culture. Typically, all components required for a xeno-free culture come from the same organism while taking care that it is completely free of animal or human elements, like bovine blood for culturing media, etc. As a replacement to these essential components, researchers are trying to synthesize new protein ligands that can function in a similar pattern4. To reiterate, genetic manipulation of the ex vivo model has the potential to save lives but requires a deeper study in the areas of limited substrate compatibility and availability. In contrast to the ex vivo model, the chimeric model revolves around cell differentiation inside a living body. Chimeras are organisms made up of a combination of two or more zygotes and thus this model introduces extraction from and cell differentiation in two different individuals. Generation of embryonic chimeras is of both practical and conceptual importance as it provides a method to assess the developmental competence of cells. The cells of the different individuals on the same embryo can be tracked and genes can be manipulated to create a chimeric organism that can act as a vessel for organ generation. Blastocyst complementation and target organ complementation are two important techniques in chimeric organ regeneration. While blastocyst complementation uses iPSCs transferred to an embryo of another species, generally a porcine embryo, target organ complementation is focused on the regeneration of specific organs of the body. Due to the unconventionality, the adherence to soci al and ethical limitations is of great importance and requires more research to be conducted. Experiments combining this regenerative model and the forced expression of the Mixl1 gene have been successful in producing organs in different hosts. By trying to reconcile the idea of targeted generation of organs derived by using the patients own PSCs as seen in the case of the mice, Kobayashi et al (2016) makes use of blastocyst complementation to create pancreatogenesisor nephrogenesis-disabled mice. Blastocyst complementation is a technique that makes use of induced human pluripotent stem cells (iPSCs) transferred to an embryo of another species; thus, following cell growth in another body. This study used Pdx1-LacZ heterozygous mice as the chimeric hosts and injected humanized pancreatic cells in the blastocyst. This complementation was followed by the forced induction and expression of the Mixl1 gene using the pRosa26-tTA-Mixl1 vector. The data was analyzed by Western blotting and flow cytometry. The immediate result showed chimeric cells throughout the bodies of the mice. The mice were then introduced to a cell medium without Doxycycline (Dox). Immunofluorescence confirmed the distribution of cells being confined to just the guts, showing that specific target organ regeneration is possible with suitable environmental conditions and resources for the culturing cells. The forced expression of the MIxl1 gene represses mesodermal fate determination and promotes endodermal fate determination, thus helping to induce the formation of target specific organs, including the pancreas or the liver, in the disabled mice. In order to test for the amount of time Mixl1 takes to express, these mice were injected with Dox at various time intervals and the results were examined using EpCAM, an endodermal genetic marker. The cell growth apex was noted on the 4t h day of Dox administration. This leads to the belief that time is an important factor in understanding cell growth in chimeric organisms. To understand the regulation of Mixl1 based on biological functions, it was allowed to express under the influence of Oct3/4, a genetic marker seen to express in early development. The absence and presence of Dox in the host chimera was compared to establish that its absence would achieve specific target organ regeneration as compared to cell growth throughout the body. The data implied that Mixl1 presence was necessary until the epiblast stage. This gives way to the inference that the time taken for Mixl1 to express can be reduced, thus giving way to a quicker technique of organ regeneration. This model, although promising, is questionable due to the ethical controversies like the formation of human neural cells or germ cells in the host animal. This is a cause for concern due to the fact that the idea of a human brain trapped inside a mute animal is disturbing. Proper manipulation of cell differentiating genes like Mixl1 is essential to keep hPSCs from turning into cells that could humanize the host animal. While understanding and experimenting on techniques that help in human advancement, there has to be a larger focus on the social and ethical concerns of utilizing them. In conclusion, although it is limited by growing ethical concerns, genetic manipulation in chimera may help save lives with the advancement in understanding cell repair and regeneration. Thus, the idea of organ regeneration using chimerism should be looked into by science but in a way that can appeal to social principles. Another problem associated with this model of regeneration is the low success rate of differentiation in non- rodent animals2. Majority chimera experiments include rodent species as the main focus, due to both the size and relatively easy manipulation of the rodents. Although recent experiments have shown (that) porcine hosts act as good carriers for human pancreatic growth6, there is a lot of research to establish pigs as conventional hPSC hosts in order to continue chimeric research to generate bigger organs like the human heart or the human lungs. While comparing the advantages and the disadvantages of both these techniques of organ regeneration, the role and function of Mixl1 itself cannot be overlooked. Mixl1 has been shown to express within 4 days of being induced. More research may lead to a quicker expression time. Mixl1 has also helped to achieve a target specific organ regeneration by promoting mesodermal differentiation as required. The use of Mixl1 is enormous in the field of regenerative biology and can be used in other projects as well as models of regeneration. In conclusion, both ex vivo regeneration and chimeric regeneration have flaws but it is possible to refine them for better and more specific results. While the usefulness of Mixl1 cannot be denied, better models of regeneration must be established to achieve maximum efficiency for its expression. References: Mostowy, S., Boucontet, L., Moya, M. J. M., Sirianni, A., Boudinot, P., Hollinshead, M., Colucci-Guyon, E. (2013). The zebrafish as a new model for the in vivo study of Shigella flexneri interaction with phagocytes and bacterial autophagy. PLoS Pathogens, 9(9) Wu, J., Greely, H. T., Jaenisch, R., Nakauchi, H., Rossant, J., Juan Carlos Izpisua Belmonte. (2016). Stem cells and interspecies chimaeras. Nature, 540(7631), 51-59. Yang, L., Wang, X., Kaufman, D., Shen W. (2011) A synthetic substrate to support early mesodermal differentiation of human embryonic stem cells. Biomaterials. 2011 Nov;32(32):8058-66. Karnieli O., Friedner O., Allickson J., Zhang N., Jung S., Fiorentini D., Abraham E., Eaker S., Yong T., Chan A., Griffiths S., When A., Oh S.A consensus introduction to serum replacements and serum-free media for cellular therapies. Cytotherapy , Volume 19 , Issue 2 , 155 169. Kobayashi, T., Kato-Itoh, M., Nakauchi, H. (2015). Targeted organ generation using Mixl1-inducible mouse pluripotent stem cells in blastocyst complementation. Stem Cells and Development, 24(2), 182. Matsunari, H., Nagashima, H., Watanabe, M., Umeyama, K., Nakano, K., Nagaya, M., . . . Nakauchi, H. (2013). Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs. Proceedings of the National Academy of Sciences of the United States of America, 110(12), 4557-4562.

Wednesday, November 13, 2019

Theories of Accident Causation Essay --

There is major concern about patient safety. It has been caused in part by obvious failures in which many patients have been harmed. This concern seems to be escalating worldwide. The medical culture that we’re in today seems to rely on secrecy, professional protection, defensiveness, and respect to authority. Theses ideologies are central to these failures, and preventing future failures depends on cultural as much as structural change in health care systems and organizations. Swiss Cheese Model James T. Reason developed the Swiss cheese model. The model is used in risk evaluations and risk management to determine accident causation. It’s an accident causation model used in aviation, engineering and healthcare. It represents the human systems used and equates them to Swiss cheese slices put side by side. Sometimes it is referred to as the cumulative act effect. The structure of the Swiss cheese model applies to most risky fields, but I will discuss how it applies to healthcare. The developer theorized that most accidents could be traced back to more than one failure. These failures include organizational influence, supervision, preconditions and specific acts. Some examples of preconditions include fatigued workers, or communication errors. Unsafe supervision can be explained as putting inexperienced nurses in an Oncology unit to administer chemotherapy. Organizational influences can be perceived as performing understaffed when the consequences are known. An organization’s guard against most failures, in the Swiss cheese model, are presented as a chain of walls, symbolized by the slices of cheese. The wholes that are in the cheese represent the weaknesses in individual parts of the healthcare system, and are constantly wavering i... ...ime or another, but if you can decrease that amount from what you normally see it could benefit your organizations reputation. Health care executives are able to better understand why keeping patients’ safe from harm protects market share, reimbursement levels, organizational reputation, and accreditation status (Carroll, 2009). Today, in almost every health care system, safety has become a top priority. Through patient safety efforts the risk management professionals can help to place trust back into the health care system. Reference Carroll, R. (2009). Risk Management Handbook for Health Care Organizations. San Fransisco, CA, USA: Jossey-Bass. Walshe, K., & Shortell, M. S. (2004, May). When Things Go Wrong: How Health Care Organizationa Deal With Failures. Retrieved January 15, 2014, from Health Affairs: content.healthaffairs.org/content/23/3/103.full Theories of Accident Causation Essay -- There is major concern about patient safety. It has been caused in part by obvious failures in which many patients have been harmed. This concern seems to be escalating worldwide. The medical culture that we’re in today seems to rely on secrecy, professional protection, defensiveness, and respect to authority. Theses ideologies are central to these failures, and preventing future failures depends on cultural as much as structural change in health care systems and organizations. Swiss Cheese Model James T. Reason developed the Swiss cheese model. The model is used in risk evaluations and risk management to determine accident causation. It’s an accident causation model used in aviation, engineering and healthcare. It represents the human systems used and equates them to Swiss cheese slices put side by side. Sometimes it is referred to as the cumulative act effect. The structure of the Swiss cheese model applies to most risky fields, but I will discuss how it applies to healthcare. The developer theorized that most accidents could be traced back to more than one failure. These failures include organizational influence, supervision, preconditions and specific acts. Some examples of preconditions include fatigued workers, or communication errors. Unsafe supervision can be explained as putting inexperienced nurses in an Oncology unit to administer chemotherapy. Organizational influences can be perceived as performing understaffed when the consequences are known. An organization’s guard against most failures, in the Swiss cheese model, are presented as a chain of walls, symbolized by the slices of cheese. The wholes that are in the cheese represent the weaknesses in individual parts of the healthcare system, and are constantly wavering i... ...ime or another, but if you can decrease that amount from what you normally see it could benefit your organizations reputation. Health care executives are able to better understand why keeping patients’ safe from harm protects market share, reimbursement levels, organizational reputation, and accreditation status (Carroll, 2009). Today, in almost every health care system, safety has become a top priority. Through patient safety efforts the risk management professionals can help to place trust back into the health care system. Reference Carroll, R. (2009). Risk Management Handbook for Health Care Organizations. San Fransisco, CA, USA: Jossey-Bass. Walshe, K., & Shortell, M. S. (2004, May). When Things Go Wrong: How Health Care Organizationa Deal With Failures. Retrieved January 15, 2014, from Health Affairs: content.healthaffairs.org/content/23/3/103.full

Sunday, November 10, 2019

How Human Activities Negatively Affect the Ecosystem Essay

In various ecosystems, negative changes have been seen as consequences of human activities. Specifically, these various activities of people have been observed to contribute directly and indirectly to the negative changes and implications in one of the major ecosystems, the marine ecosystem. This paper suggests that many of the human activities employed in the environment, specifically the marine ecosystem, yield multiplicative detrimental effects. It is said that humans have a high influence over ecosystems, and the various activities they make alter the environment’s conditions (Millennium Ecosystem Assessment, 2003). According to Hylland (2002), there are many different perspectives that could affirm the impact of human activities towards nature. However, in purely simplistic illustrations, human activities that involve physical disturbance, release of harmful chemicals, and other destructive forms cause serious effects such as a reduced biodiversity. Physical disturbances such as trawling, large scale fishing, or coastal construction prevent fish and other marine species from staying in their original habitat. This means that these marine fauna are displaced from their habitat which may have been destroyed or changed beyond recovery by drastic fishing activities made by man. Similarly, the marine ecosystem may not only be lessened because of the displaced marine organisms, but it is also possible that an eventual decrease in the population level of these organisms may happen. This could trigger to a relatively damaging human activity wherein humans will aim for the fish nearer the coastal areas. Under many legislation proceedings, fishing near the coastal areas is prohibited because the act will strip the number of fish and other marine species into a minimal number. Over-fishing could as well cause the decrease in the biodiversity of marine animals (Hylland, 2002). The use of chemicals in fishing could also destroy not only the marine species but also their habitat and where eventually, humans will also be affected. This is a chain-like series of events that could lead into a negative effect, destruction even, among marine biological ecosystems. Cyanide and other dynamite fishing are often used by fishermen as an easier method of fishing that kill even the smaller fish. If these methods continue, the marine species will no longer be sustained. The chemical by products from these methods also destroy their natural ecosystem by contaminating changes that are harmful to the lives of these species. Similarly, there are instances where pollutants and toxic materials from pesticides go as water run-off from residential and agricultural areas toward the seas and other water forms, thereby contaminating the seas and the living organisms in it with the toxic substances (Hylland, 2002). Another major implication that is currently of relevance is the aftereffect of negative human activities that characterize an indirect implication: climate change. Because of the ensuing pollution, forest denudation and other factors, climate change and global warming have been relatively causing damage. These have negative effects as well on the marine ecosystems as the seas are heating up, thereby changing the distribution of species (Hylland, 2002). Conclusively, it must be noted that many various human endeavors have multiplicative detrimental effects to many ecosystems, specifically the marine ecosystem. As mentioned, the negative effects do not only encompass the destruction of the marine ecosystems but also the biodiversity of the marine species. When the habitats are destroyed, the number of marine organisms decreases, therefore catapulting to unsustainability in the ecological balance. This goes to show that every human activity that has negative impacts will be felt multiplicatively through direct and indirect measures. References Hylland, K. (2002, February). How [Do] Human Activities Affect Marine Biodiversity And Ecosystem Processes? Paper presented at the The EC IMPACTS Cluster First Workshop. Universite de Pau et des Pays de l’Adour, Pau cedex, France. Retrieved April 2, 2009 from http://web. univ-pau. fr/impacts/Theme2part1. pdf. Millennium Ecosystem Assessment. (2003). Ecosystems and Human Well-being: A Framework for Assessment. Washington DC: Island Press.

Friday, November 8, 2019

Free Essays on Business Organization

The demands of the 21st century will require business organizations to become more customer and stakeholder focused, using employee talent to create, share, and utilize information as part of a broadbased competitive strategy. Another part of this transition will see organizations undergoing significant structural change, developing horizontal networks of taskfocused teams leading to "delayered," flatter organizational structures. The horizontal organization will be (1) organized around processes rather than tasks, (2) driven by customer needs and inputs, and (3) dependent on team performance.1 As networks of teams replace traditional hierarchies, knowledge becomes the main organizational resource.2 As part of the rapid, often tumultuous, change in the global business world, organizations will, therefore, have to speed up their learning processes, learning how to adapt faster and faster to the world around them. Teams, as well as teams of teams, will need to learn how to develop such knowledge bases, in essence learning, how to learn together, effectively sharing, information and building, on each other's knowledge to create generative rather than simply adaptive learning patterns.3 Accordingly, open communication creating shared meaning and understanding among team members as well as among, teams will be one of the most critical skills for organizational members. The ability to facilitate such teams and create an organization that can effectively use them will also be an important management skill.... Free Essays on Business Organization Free Essays on Business Organization The demands of the 21st century will require business organizations to become more customer and stakeholder focused, using employee talent to create, share, and utilize information as part of a broadbased competitive strategy. Another part of this transition will see organizations undergoing significant structural change, developing horizontal networks of taskfocused teams leading to "delayered," flatter organizational structures. The horizontal organization will be (1) organized around processes rather than tasks, (2) driven by customer needs and inputs, and (3) dependent on team performance.1 As networks of teams replace traditional hierarchies, knowledge becomes the main organizational resource.2 As part of the rapid, often tumultuous, change in the global business world, organizations will, therefore, have to speed up their learning processes, learning how to adapt faster and faster to the world around them. Teams, as well as teams of teams, will need to learn how to develop such knowledge bases, in essence learning, how to learn together, effectively sharing, information and building, on each other's knowledge to create generative rather than simply adaptive learning patterns.3 Accordingly, open communication creating shared meaning and understanding among team members as well as among, teams will be one of the most critical skills for organizational members. The ability to facilitate such teams and create an organization that can effectively use them will also be an important management skill....

Wednesday, November 6, 2019

Advertisements and De Destruction essays

Advertisements and De Destruction essays In the movie, Advertising and the end of the world, Sut Jhally talks about how advertising is affecting the world negatively. In the beginning of the movie Jhally talks about advertising as a culture. And how physical and simple things dont apply. Jhally stated that if an anthropologist came from mars and based our culture off of advertisements, they would think that we believe in magic, and that normal doesnt apply to us. Some advertisements even come into our personal lives and change our culture. He gives DeBeers as an example of how they have intruded into our lives. Later, Jhally talks about how the advertisements show people as being happy if we buy the product. Advertising tells us that the more we buy the happier we are going to be. Jhally gave us some statistics that show our happiness levels and our wealth levels. And our wealth has gone up but our happiness has stayed the same. Jhally then discusses a survey that they did, and asked people what made them happy. More often than not people said social things and not physical things. Social things are like friends, families, autonomy control, romance, self esteem, and relaxation. Physical things are like economic status, and houses. In the movie Jhally says that products cant provide you with social things, only material. Advertisements are used everywhere. And each one was expensive to make, ads are more expensive per thirty seconds than the biggest blockbuster hit. Jhally gave an example of Jurassic Park and how much it cost in comparison to an advertisement. The movie was something like 236 thousand dollars every thirty seconds an the commercials averaged at about 247 thousand dollars. An example he gave for commercials going to extremes, was the Timex commercial where they flew set builders in from England to the Red Sea to make a two story model of a watch. Now commercials have to do that sort of thing ...

Monday, November 4, 2019

Batman Essay Example | Topics and Well Written Essays - 2000 words

Batman - Essay Example By comparing the politics of the Batman series to other original series, a series featuring an abundance of similar themes as well as academic and political regard, his creative innovations stand out as spectacular (White & Robert 73). Therefore, I plan to argue not only that the film acts as a political magnifier, but also how Batman is one of the best movies over the last decade and how Batman series are better than other movie series. First, in the Batman films, Director Burton has created a wicked world of misfits as compared to any other current film in the industry. In his production, all of the films bring out a mixture of horror, sympathy, and playfulness (Hatfield & Kent 59). The director’s innovative brain in the films stands out as his hallmark, a spectacular input that has branded the collections of Batman as of more public demand than any other film of late. As to affirm this proposition, an excerpt from New York Times describes some of the inside brains behind th e success of the films as outstanding. For example, Michael Keaton features a person who has brought appropriate earnestness in the production of the films. As for Danny DeVito, he stands out as the conveying nerve while Christopher Walken as a ‘wonderfully debonair’. The resonating nature of Batman productions does not augur well without the mention of Michelle Pfeiffer who has remained as a captivating, fierce, and seductively ruthless actor as Batman uses these actors to ride the audiences back to the liberating darkness of dreams (White & Robert 84). This is what made a movie like Batman Returns as the summer’s most explosive and captivating film/movie. For example, as for the actor Michelle Pfeiffer, Batman stitches so good the feminist avenger of a tough core of intelligence in her role. This classic dazzler role pins these movies at the charts of the most interesting innovation the industry has had to sell to the public (Langley 88). This has placed Batman creativity at the best of all. In his masterpiece movie, Returns, Batman accomplishment lies in the amazing physical realization of an imaginative universe. Through his director Burton, he not only re-creates his one of a kind atmosphere but also ones-up it, and even two-ups it as well. This evokes the psycho-murky worlds in which the characters operate and reside. For example, Penguin holds court in a penguin-crowded, Phantom of the opera like sewer home (White & Robert 92). One can also realize that Keaton hides in a castle like mansion as this brings out the owner’s inner remoteness. This movie creates a seamlessly, utterly consistent universe filled with nasty notions. It captures the immediate societal degradation, greed and other base impulses, themes which incarcerate the immediate context the audience's brush shoulders with hence making the film/movie not only relevant but also feasible in the world we are living (Langley 76). This has made Batman movie Return famous even though critics have found its anti-Semitic overtones in Penguins character not appealing. Batman series is objectively better than any other superhero stories. Like many arguments online, Batman series is built up by intelligence and careful preparation. Batman’s regular stories are interesting making it the best series that

Friday, November 1, 2019

Final assignment Example | Topics and Well Written Essays - 1250 words - 1

Final - Assignment Example As the rate of globalization goes high in the United States, the developing countries also look forward to get them same effects of globalization. Thus, the United States of America has to play a major role in facilitating development in the third world countries. United States created two international institutions which aim at developing all the countries in the world. The two institutions are World Trade Organization (WTO) formed in 19951. The main function of the World Trade organization was to settle all the trade disputes among the countries in the world. The second organization is the International Monetary Fund (IMF) which was formed after World War II. The events of the war destroyed most of the countries’ resources, and something had to be done to revolve their economy. The International Monetary Fund provided emergency loans to countries. After the events of World War II, the United States of America plays a major role in shaping the economy of the world. Thus, to ensure that other countries develop, they have to incorporate all the aspects of globalization. They have to advance the living standards and ensure that there is stability in the world’s economy. The policy makers have to come up with policies that promote globalization in all the countries, which is a great challenge2. Consequently, some of the third world countries cannot adapt globalization because of factors such as illiteracy and poverty. The United States has first to work on the two major challenges before introducing globalization in those countries. Thus, they need resources to ensure that they provide all the basic needs required and improve their education sector. Finance is needed to carry out all these activities, making it a great challenge. Globalization has resulted in a faster exchange of ideas among the countries. Criminals use the advanced technology to communicate over a long